Check out Stacey's book: The World's Worst Diabetes Mom!
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Episode Transcription Below (or coming soon!)
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Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines of the past seven days. we go live on social media first and then All sources linked up at diabetes dash connections dot com when this airs as a podcast.
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The news is brought to you by The World's Worst Diabetes Mom: Real Life Stories of Parenting a Child With Type 1 Diabetes. Winner of best new non-fiction at the American Book Fest and named a Book Authority best parenting book. Available in paperback, eBook or audio book at amazon.
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Our top story is a very interesting LinkedIn post about a new company and product.. Luna Diabetes aims to fill in a big gap – overnight automated control for people who use smart insulin pens. They’re calling it A-I – automated injections, a way to combine the convenience of insulin pens with the clinical outcomes of automated insulin delivery – like Control IQ or Looping. Some heavy hitters here – the founders are John Show-lund Sjolund – founder of Timesulin, John Brilliant a co-founder of BigFoot biomedical and Sean Saint, founder of Companion Medical who made the InPen automated pen system. The release shows a little device but no real information yet. Is it an automated basal delivery system for overnights only? pivotal trial to start by the end of this year We’ll keep you posted..
https://www.lunadiabetes.com/
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A look at pediatrics in under-served communities shows most children are not meeting A1C goals. A new grant from the Helmsley Charitiable Trust will focus on expanding access through remote care. Many providers lack the money to set remote care up and use it effectively – telehealth systems and things like that. A large pediatric endo group in Buffalo, NY will work with Cecelia Health, a virtual first health care provider. They’ll work with about a thousand patients to explore how improving access to remote support and the internet to better manage chronic conditions will improve outcomes. This is along with existing diabetes technology like pumps and CGMs.
https://www.benzinga.com/pressreleases/22/04/n26682238/improving-outcomes-for-children-and-adolescents-living-with-type-1-diabetes-is-the-goal-of-a-colla
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Big news for people with diabetes in Australia. The government has committed to subsidized access to continuous glucose monitoring and flash glucose monitoring technology for all people living with type 1 diabetes. Right now, people under 21 are already eligible as as women who are actively planning a pregnancy or are pregnancy. This agreement will make everyone eligible for just over 30-dollars a month. Right now it costs over 300-dollars a month. I’m going to link up info from the incredible Diabetes Australia advocate Renza Scibilia who’s been on the show before and who’s been working on this for more than ten years. Congrats Renza and all who will benefit.
https://www.diabetesaustralia.com.au/mediarelease/diabetes-australia-welcomes-bipartisan-commitment-to-cgmforall/
https://diabetogenic.blog/2022/04/17/oh-happy-day/
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Not a big surprise but important information about improving life expectancy in people with type 2. New study shows reducing A1C, blood pressure, cholesterol and BMI makes a big difference. This was a University of Florida Gainesville study.. biggest improvement in all of these was reducing A1C from the highest in the study – about 9.9 - to the lowest about - 7.7 - added almost 4 years of life expectancy. These researchers say it’s very motivating to patients and clinicians to see these gains and it may help them choose treatment goals.
https://medicalxpress.com/news/2022-04-treatment-goals-diabetes-life.html
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We’ve talked about One Drop before.. more than a meter, they now call themselves a digital coaching company. And a new evaluation from an independent, third-party found that One Drop’s support program effectively improves the health of people living with prediabetes, diabetes, and high blood pressure. The program could also cut down on annual healthcare costs. This is from the independent Validation Institute, dedicated to providing unbiased, data-driven insights on health care solutions. The Validation Institute financially guarantees the program’s effectiveness. This means that people who follow the program properly but do not improve their blood pressure or A1C can file a claim with Validation Institute for up to $25,000.
https://diatribe.org/one-drop-results-backed-by-independent-review
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Okay this newscast is going live on April 20th.. or 4-20.. There are a lot of questions about whether marijuana which is now legal in a lot of the US is okay to use if you have diabetes. I’m going to link up some information for you in the show notes.. But most of the information focuses on the slightly altered state weed can put you in.. for many that means being more relaxed but for some it may interfere with diabetes management in the moment. There’s nothing specifically good or bad about marijuana that I could find for people with diabetes. However there is a warning for any pregnant woman -children who were exposed to cannabis in utero may be at risk for obesity and high blood sugar later in life.
https://beyondtype2.org/marijuana-and-type-2-diabetes/
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On this week’s long format episode, Dr Mark Heyman is a diabetes psychologist who lives with type 1. He has great advice for the most under-treated part of diabetes, the mental health aspect of it all. Next week you’ll hear from Civica RX – this is the company pledging to put out insulin without making a profit. We’ll hear why they think this will work and how soon it’ll be available for purchase.
Listen wherever you get your podcasts
That’s In the News for this week.. if you like it, please share it! Thanks for joining me! See you back here soon.
We don’t need to tell you that the mental burden of diabetes is a heavy one. And most of us – caregivers and people with diabetes alike - are never given any resources to help. My guest this week is trying to help.
Dr. Mark Heyman is a diabetes psychologist and lives with type 1 himself. His new book is called “Diabetes Sucks, and You Can Handle It.” We talk about why he wanted to write the book, who it’s for and what we can learn from his experiences. talk about some of the common fears and worries he hears and what he advises his patients.
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
Check out Stacey's book: The World's Worst Diabetes Mom!
Join the Diabetes Connections Facebook Group!
Sign up for our newsletter here
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Use this link to get one free download and one free month of Audible, available to Diabetes Connections listeners!
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Episode Transcription Below (or coming soon!)
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Sage Donnelly started kayaking with her father at age two, when he'd sit her in the boat next to him. She was diagnosed with type 1 diabetes at age 3 and got right back in the water. After watching competitions for several more years, at age seven she told her parents she wanted to compete. She wasn't kiddng!
Donnelly was the Jr. Women’s Freestyle World Championship and earned a spot in the Olympics. More recently, she's decided to go in another direction and shares what prompted the change. We talk about how she keeps her diabetes gear protected in the water, treating lows during 3-day remote adventures and more.
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
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Check out Stacey's book: The World's Worst Diabetes Mom!
Join the Diabetes Connections Facebook Group!
Sign up for our newsletter here
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Use this link to get one free download and one free month of Audible, available to Diabetes Connections listeners!
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Episode Transcription Below (or coming soon!)
Please visit our Sponsors & Partners - they help make the show possible!
It’s “In the News…” Got a few minutes? Get caught up! Our top stories this week include testing a new treatment for leukemia to see if it might help with type 1, Black patients with type 1 are at higher risk of DKA, transitioning from teen care to adult care, updates on Eversense in the US and Dexcom One in the UK and front office changes at Beyond Type 1 and Vertex.
Check out Stacey's book: The World's Worst Diabetes Mom!
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Sign up for our newsletter here
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Use this link to get one free download and one free month of Audible, available to Diabetes Connections listeners!
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Episode Transcription Below (or coming soon!)
Please visit our Sponsors & Partners - they help make the show possible!
Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines of the past seven days. we go live on social media first and then All sources linked up at diabetes dash connections dot com when this airs as a podcast.
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The news is brought to you by The World's Worst Diabetes Mom: Real Life Stories of Parenting a Child With Type 1 Diabetes. Winner of best new non-fiction at the American Book Fest and named a Book Authority best parenting book. Available in paperback, eBook or audio book at amazon.
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Interesting look at whether a treatment for leukemia might work against type 1. Very early on here.. but AVM Biotechnology has received a grant to find out. The drug doesn’t have a name yet.. it’s referred to as AVM-0703 and has been shown to delay T1D in the lab.
A preclinical dose-finding and mechanism of action (MOA) study in three scenarios including pre-diabetic, new-onset, and established diabetes is the first aim of the program. Those results will be used to determine the targeted dose to be used in a pivotal efficacy study for reversal of new-onset and established diabetes. It is anticipated that for patients not showing remission, AVM0703 may reinforce other immunotherapies allowing a wider range of patients to achieve insulin independence.
https://www.businesswire.com/news/home/20220405005529/en/AVM-Biotechnology-Awarded-1.6-Million-Phase-II-SBIR-Grant-to-Study-AVM0703%E2%80%99s-Potential-to-Reverse-Type-1-Diabetes
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Black patients with type 1 faced a significantly higher frequency of diabetic ketoacidosis during the pandemic, and particularly during surges, researchers reported. This was a big study at several different health centers and hospitals. Researchers found there was not significant difference in the number of patients in DKA from 2019 versus 2020.. but there was a higher proportion of Black patients. The trend continued through the pandemic and again, it was significant, 48-percent versus 18 percent. Pandemic surges emphasized the disparity even more. These researchers say their work shows racial inequities in diabetes care were present before the pandemic, starkly visible during the pandemic, and will continue to persist after the pandemic -- unless we systemically root out and target racial inequities in diabetes care,"
https://www.medpagetoday.com/endocrinology/type1diabetes/98044
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A new look the transition from pediatric to adult care for people with type 1 shows.. it needs improvement. This research – based on interviews with older adolescents showed many felt unprepared and dissatisfied with the transition process. Three big takeaways – the teens are aware of the changing relationship with their parents and health care teams and often want more independence than the parents are willing to give… the teens want acknowledgement that being diagnosed at different ages means they may be more or less comfortable with self-management and the third is that they think their pediatric team isn’t preparing them to work with adult providers. Personally, this means a lot to me – as my son is 17 – and I’ll be asking his peds endo to work with him more on this stuff in the next couple of years.
https://www.healio.com/news/endocrinology/20220401/novel-programs-needed-to-improve-transition-from-pediatric-to-adult-diabetes-care
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DiabetesWise announces the launch of it’s new Pro website. It’s an unbranded non-biased resource created at Stanford University to help make providers more informed about diabetes devices and streamline the prescription process. We’ve talked about Diabetes Wise before and I’ll link it up here. It’s easy to feel overwhelmed by the evolving choices and providers are in the same situation.
The DiabetesWise Pro website has an extensive Device Library where providers can learn about all of the FDA-approved diabetes devices on the market based on the patient’s considerations. The user can compare the devices from the different manufacturers using the Compare Device tool, which displays a side-by-side analysis of the components and details of each technology, including the steps for ordering and prescribing the device. Providers can then build a comparison report of the two devices to share with their patients, colleagues, and community.
Along with the Device Library, providers can receive help with ordering and prescribing the devices for their patients using the Prescription Tools feature on the website. The Prescription Tool directs the user to a guide providing accurate up-to-date information on the necessary steps for filing a prescription and ordering the device for the patient. DiabetesWise Pro has plans to update the tool to include details on the approval of devices for patients based on insurance type.
DiabetesWise Pro website features for use in clinic include:
1. Device Library- Information on specific device fundamentals
2. Comparison Tool- Comprehensive tool that allows you to compare device recommendations and share with patients
3. Prescription Tool- A step-to-step guide for ordering the device and filling a prescription based on insurance type
4. Resources for providers by providers- best tips, tricks, and workarounds for diabetes technology from providers
With this new resource, there have also been enhancements to the patient-facing website at DiabetesWise. Newly approved devices have been added and there are now Spanish-language versions of the Check-Up and Device Finder.
https://diabeteswise.org/#/
https://providers.diabeteswise.org/#/
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FDA approval in February, now the Eversense six-month CGM is rolling out to patients. The price is set at 99-dollars out of pocket for the first transmitter and sensor and then $100 per month for the six months of wear. The device includes a small fluorescence-based sensor, about the size of a grain of rice, which is fully embedded in the upper arm. A transmitter stuck to the skin over the sensor reads the data, transmits the information to a smartphone and provides vibration alerts for changes in blood sugar.
https://www.fiercebiotech.com/medtech/ascensia-diabetes-care-launches-eversenses-6-month-cgm-system-us
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Dexcom ONE is getting a big roll out in the UK. We’ve talked about this a couple of times in the past.. it’s the same Dexcom technology but a bit pared down and at lower cost. This news comes as the National Institute for Health and Care Excellence (NICE) announced new guidance for adults and children managing Type 1 diabetes. NICE now recommends that adults with Type 1 diabetes be offered a choice of glucose sensors. G6 is already offered there and the G7 will be as well, but this is about national health service coverage, and the Dexcom One is the only system under consideration there.
https://www.businesswire.com/news/home/20220401005092/en/Dexcom-Announces-Dexcom-ONE-the-Newest-Real-Time-Continuous-Glucose-Monitoring-System-to-Its-Range-of-Scan-Free-and-Fingerprick%E2%80%A0-Free-Devices
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Some front office news around the community..
Stem cell pioneer Doug Melton is leaving Harvard to join Vertex Pharmaceuticals. Not entirely unexpected – Melton’s company Semma was purchased by Vertex and they are moving ahead toward stem cell transplantation as a functional cure for type 1. This was the company that got all those headlines last fall about the cure – you remember “It worked in this one guy!” Melton is joining the company as a distinguished Vertex Fellow. Semma, by the way, was named after his two adult children who live with type 1 – Sam & Emma.
https://www.statnews.com/2022/04/05/douglas-melton-noted-stem-cell-researcher-leaves-harvard-for-vertex-to-create-diabetes-treatments/
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Beyond Type 1 names Deborah Dugan as CEO. She replaces Thom Scher who died suddenly and unexpectedly in December. Dugan was previously the CEO of RED, the not-for-profit organization founded by U-2’s Bono (bah no) and Bobby Shriver to raise awareness in the fight against AIDS. Dugan, has been recognized as one of the "100 Most Powerful Women" by Forbes, "Top Woman to Help Change the World" by Elle and as a "Nelson Mandela Changemaker"
https://beyondtype1.org/beyond-type-1-diabetes-deborah-dugan-ceo/
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Congratulations to Leo and Alana Folsom who welcome a baby boy. The couple was on a recent season of the Amazing Race and after we all saw Leo’s Dexcom in one of the first episodes, he came on this show to share his story. Leo lives with congenital hyperinsulinism, where the body makes too much insulin, and had almost his entire pancreas removed. He told me at the time he was amazed by the diabetes community’s support. So I just wanted to say congrats to him and to Alana and help welcome baby Kitt Edwin Folsom.
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On this week’s long format episode, Laurie Harper shares her story… Laurie was diagnosed as a toddler back in 1955. She’s in the Joslin Medalist Study and talks about the difference this incredible group is making. Next week you’ll hear from World Champion Kayaker Sage Donnely who was diagnosed with type 1 at age 3 when she’d already been kayacking for almost a year.
Listen wherever you get your podcasts
That’s In the News for this week.. if you like it, please share it! Thanks for joining me! See you back here soon.
It’s always a privilege to talk to one of the Joslin Medalists. This week you’ll hear from Laurie Harper. She was diagnosed as a toddler in 1955 and will mark 67 years with type 1 later this year. She shares what she remembers about her early years with diabetes, how her family adjusted, the technology she started with and what she uses now.
The Joslin Medalist program recognizes and studies people who’ve lived with type 1 for at least 50 years. Laurie tells us more about the medalist program, about aging with diabetes and she takes a look back at how different the management was almost 70 years ago.
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
Learn more about the Joslin Medalist Program
Check out Stacey's book: The World's Worst Diabetes Mom!
Join the Diabetes Connections Facebook Group!
Sign up for our newsletter here
-----
Use this link to get one free download and one free month of Audible, available to Diabetes Connections listeners!
-----
Episode Transcription Below (or coming soon!)
Please visit our Sponsors & Partners - they help make the show possible!
It’s “In the News…” Got a few minutes? Get caught up! Our top stories this week include new information about the temperature at which insulin can be safely stored, a warning about men taking Metformin, news about sexual health and women with diabetes, and a heads up about a virtual mental health conference coming up for people with diabetes.
Check out Stacey's book: The World's Worst Diabetes Mom!
Join the Diabetes Connections Facebook Group!
Sign up for our newsletter here
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Use this link to get one free download and one free month of Audible, available to Diabetes Connections listeners!
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Episode Transcription Below (or coming soon!)
Please visit our Sponsors & Partners - they help make the show possible!
Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines of the past seven days. we go live on social media first and then All sources linked up at diabetes dash connections dot com when this airs as a podcast.
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The news is brought to you by The World's Worst Diabetes Mom: Real Life Stories of Parenting a Child With Type 1 Diabetes. Winner of best new non-fiction at the American Book Fest and named a Book Authority best parenting book. Available in paperback, eBook or audio book at amazon.
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Our top story.. a look at how insulin holds up under real-world and often hotter conditions than is recommended. Doctors without Borders found that a range of insulins can be stored at warmer temperatures than previously recommended. They showed it’s okay above 77-degrees all the way up to 99 degrees for four weeks. This is really important not just for emergency settings like refugee camps but for people who live in areas without refrigeration. They often have to travel to health clinics which may be far away and which can’t send them home with the insulin. The group now says pharmaceutical corporations should urgently submit to regulatory authorities for use of insulin under expanded temperature ranges. This came out a few weeks back, but I haven’t seen it anywhere.
https://www.doctorswithoutborders.org/latest/msf-study-shows-some-insulin-can-be-stored-warmer-temperatures
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Big headlines this week about Metformin and the risk of of birth defects in the babies of men who take it. Metformin is a very common diabetes drug, taken by tens of millions of people around the world. Sons born to men taking it were more than three times as likely to have a genital birth defect as unexposed babies. These problems were relatively rare, occurring in fewer than 1-percent of all babies with dads who took Metformin but it’s significant because tens of millions of people worldwide take metformin. These researchers say the paper’s findings are preliminary and observational only.. and that men with diabetes should NOT abruptly stop metformin before trying to conceive. Reassuringly, the researches saw no effect for men who took the drug earlier in life or even a year before. Expect a lot more research to come on this one.
https://www.science.org/content/article/rare-genital-defects-seen-sons-men-taking-major-diabetes-drug
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Grain of salt needed here, but new research may show that people with type 1 are more likely to manage better if they have high levels of psychological resilience. This was a British study that followed 18-hundred people with type 1 or type 2 diabetes. They used a questionnaire to determine how they adapted to change and focused under pressure. The researchers found that people with type 1 diabetes who had low psychological resilience also had poorer blood sugar control after two years. The idea is that something like this would offer the opportunity to identify those who might benefit most from additional support when they are first diagnosed.
https://medicalxpress.com/news/2022-03-psychological-resilience-future-high-blood.html
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Among patients with diabetes, women are just as likely as men to suffer from sexual dysfunction, but their issues are overlooked. Big session on this at the Diabetes UK Professional Conference this week. Reserachers say women with diabetes can experience reduced sexual desire, painful sex, and other issues which can increase the risk of depression. But these issues are usually untreated despite help being available. They talked about the embarrassment factor and the idea that many women with sexual dysfunction don’t realize diabetes could be a factor.
They encourage health care professionals to go beyond conversations about contraception, pregnancy and menstruation. A recent study led by Belgian researchers found that among more than 750 adults with diabetes 36% of men and 33% of women reported sexual dysfunction.
https://www.medscape.com/viewarticle/971208
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Concerning new trend about pre-diabetes.. it’s doubled among children over the last 20 years. The increase was seen over almost all subpopulations of young Americans, regardless of income, ethnicity and education. The study in the journal JAMA Pedatirics included kids 12 to 19 years old from 1999 to 2018. The rate of presdiabetes went from 11.6-percent to 28.2-percent. Pre-diabetes means blood glucose levels are higher than normal but not yet at the diabetes threshold. These researchers are quick to point out, they don’t know the reason why this is happening.. while diet and exercise are usually what’s pointed to.. it’s not entirely clear that’s the reason behind this rise.
https://www.cnn.com/2022/03/28/health/prediabetes-children-study-wellness/index.html
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Huge new study of more than 3-million people says people with type 2 have a higher risk of 57 other health conditions. Experts described the findings as stark and alarming and said it underlined the urgent need to reduce the risk of more people developing type 2 diabetes. The study, which is yet to be peer-reviewed, focused on people over 30. These researchers say the higher risks occurred when people were diagnosed with type 2 diabetes under the age of 50.
https://www.theguardian.com/society/2022/mar/29/type-2-diabetes-results-higher-risk-57-other-conditions-study
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Want to let you know about the Diabetes plus Mental Health virtual conference coming up in May. This two-day event will highlight ways in which living with diabetes affects mental health. There will be 2 tracks - one for patients and one for caregivers and providers. I’m excited to take part – just in a light hearted way. I’ll be hosting a game show type session where you can meet some of the presenters and participants. Lots more information lined up.. registration is open now and early bird pricing ends April 3rd.
https://dmhconference.vfairs.com/?fbclid=IwAR2BiuxasHL0bBGe_6JpDzMnhY__kr6HptYFGpfdwEO0ftDL7pTbMyFycIY
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On this week’s long format episode we’re talking to JDRF about the new non-profit insulin they’ve backed. Why will this effort from Civica RX be different? We’ll talk about it. Next week we’ll have a conversation with one woman in the Joslin Medalist Study. Diagnosed nearly 70 years ago she shares her story and why she’s excited about part of this incredible group.
Listen wherever you get your podcasts
That’s In the News for this week.. if you like it, please share it! Thanks for joining me! See you back here soon.
There's a new plan to manufacture and sell insulin at a much lower list price. The company behind it is non-profit Civica RX, which has support from JDRF.
Stacey talks to JDRF CEO Aaron Kowalski about what their role is here, how realistic this plan is, who it may help and a lot more. They also spend some time talking about the reorganization of JDRF and what the future after COVID 19 looks like for them.
More about Civica's Plan (we'll talk to them in a future episode)
Here's the episode Stacey references with Thom Scher and Aaron Kowalski
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
Check out Stacey's book: The World's Worst Diabetes Mom!
Join the Diabetes Connections Facebook Group!
Sign up for our newsletter here
-----
Use this link to get one free download and one free month of Audible, available to Diabetes Connections listeners!
-----
Episode Transcription Below (or coming soon!)
Please visit our Sponsors & Partners - they help make the show possible!
Check out Stacey's book: The World's Worst Diabetes Mom!
Join the Diabetes Connections Facebook Group!
Sign up for our newsletter here
-----
Use this link to get one free download and one free month of Audible, available to Diabetes Connections listeners!
-----
Episode Transcription Below (or coming soon!)
Please visit our Sponsors & Partners - they help make the show possible!
Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines of the past seven days. we go live on social media first and then All sources linked up at diabetes dash connections dot com when this airs as a podcast.
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The news is brought to you by The World's Worst Diabetes Mom: Real Life Stories of Parenting a Child With Type 1 Diabetes. Winner of best new non-fiction at the American Book Fest and named a Book Authority best parenting book. Available in paperback, eBook or audio book at amazon.
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People who recover from a mild case of COVID-19 appear to have an increased risk for subsequent new-onset type 2 diabetes… but not other types of diabetes. This is from a big new study in Germany. It lines up with previous studies of more seriously ill patients with COVID 19 who had increased rates of type 2 in the months following. This was more than 35-thousand patients – no prior history of diabetes. The risk of developing type 2 increased by 28-percent if the person had COVID, again even a mild case. The researchers say anyone who tested positive for COVID should be aware and get screened for diabetes in the months and years following.
https://www.medscape.com/viewarticle/970600
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Big new study that – interestingly – talks about the CGM as a telehealth device. It looked at how doctors continued to care for children with type 1 before and after the first year of the COVID pandemic. The use of CGMs increased significantly among those with non-commercial insurance… from 24 percent in 2019 to 35 percent by the end of 2020.
Another finding in this same study.. those with higher A1Cs, racial minorities, and those with non-commercial insurance were more likely to have high rates of DKA. But the implementation of telehealth and CGMs increased parental oversight which resulted in better care at home and lower than expected hospitalization rates. I want to dig a little deeper here because a lower hospitalization rate during the first year of the COVID pandemic overall.. was found to be tied to a lot of fear about going to a hospital during that time.
https://mhealthintelligence.com/news/telehealth-helped-maintain-type-1-diabetes-care-among-kids-during-pandemic
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Swiss pump maker Ypsomed announces the software they’ll use for their automated insulin delivery. Ypsomed will partner with CamDiab’s CamAPS app. The launch will start in select major countries in Europe, with other territories to follow over the course of 2022. This includes a hybrid closed loop – like Omnipod 5 and Control IQ - as well as smartphone control.. it’s compatible with Dexcom’s G6. It’ll start on Android then roll out on iOS.. Ypsomed is partnering with Lilly to come to the US – we’ve had them on the show before talking about this. They hope to submit to the FDA this year.
https://www.drugdeliverybusiness.com/ypsomed-partners-with-camdiab-on-smartphone-based-automated-insulin-delivery/
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The FDA is due to make a decision on Teplizumab by August 17th. This is a drug that has been shown to delay type 1 diabetes. Last year the FDA turned down Provention Bio, asking for a resubmission with more information. The company is also running the phase 3 PROTECT trial of teplizumab. That’s in newly-diagnosed type 1 diabetes patients. They hope to expanding the indications for the drug.
https://pharmaphorum.com/news/fda-sets-august-decision-date-for-proventions-type-1-diabetes-drug/
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More study underway into the tuberculosis vaccine as a treatment for type 1. This is Dr. Denise Faustman’s lab – they’re recruiting 150 teen with type 1 for pediatric clinical trials of the shots. Faustman’s work is controversial because her studies have been very small and many experts say they don’t show significant improvement. But Faustman says the vaccine appears to help patients with Type 1 diabetes by altering their immune system and that even though no one in her trials is off of insulin, there is improvement.
https://www.bostonglobe.com/2022/03/21/metro/could-100-year-old-vaccine-treat-type-1-diabetes-mgh-researchers-are-working-find-out/
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If you’re watching live, today is the last day to back the Kickstarter for Type 1 The Movie. We talked about this on last week’s podcast episode – Noah Averbach Katz is an actor who lives with type 1 and is making a movie where diabetes is front and center. Since Noah and his wife are on Star Trek Discovery, that community has jumped in to really amplify this. It’s been great to see and he’s well over his goal. If you’re watching or hearing this after March 23rd, you can follow the link anyway to stay up to date on the project. I gave and I’m excited to see how it all turns out!
https://www.kickstarter.com/projects/noahak/type-1?ref=thanks-tweet
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On this week’s long format episode we’re going on a deep dive about stem cell research with the folks at Viactye. They’re working on two fronts now.. encapsulation AND gene editing with the people at CRISPR. Next week you’ll hear from JDRF about the new non-profit insulin they’ve backed. Why will this effort from Civica RX be different? We’ll talk about it.
Listen wherever you get your podcasts
That’s In the News for this week.. if you like it, please share it! Thanks for joining me! See you back here soon.
There’s been a lot of excitement recently about stem cell transplants and progress toward using this as a functional cure for type 1. There are a few separate groups working on this, this week we're talking to ViaCyte to get past the hype and look at the real progress here.
You'll hear from ViaCyte’s Head of Clinical Development Dr. Manasi Jaiman. ViaCyte has been studying stem cell transplants for several years – and recently started working with the gene editing technology CRISPR. We’re going to talk about what this is all about, how close they really are, and who would even be in line to benefit.
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
Check out Stacey's book: The World's Worst Diabetes Mom!
Join the Diabetes Connections Facebook Group!
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It’s “In the News…” Got a few minutes? Get caught up! Top stories this week: Dexcom G7 approved in Europe, JDRF speaks out on non-profit insulin plan, Ukraine diabetes aid progress, texting for T2D, Reaction to Pixar's Turning Red
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Please visit our Sponsors & Partners - they help make the show possible!
Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines of the past seven days. we go live on social media first and then All sources linked up at diabetes dash connections dot com when this airs as a podcast.
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The news is brought to you by The World's Worst Diabetes Mom: Real Life Stories of Parenting a Child With Type 1 Diabetes. Winner of best new non-fiction at the American Book Fest and named a Book Authority best parenting book. Available in paperback, eBook or audio book at amazon.
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Our top story this week.. Dexcom gets the CE Mark for it’s new G7 system, which means it’s approved in Europe. The approval is for people ages 2 and up, including pregnant women. I’m putting the full screen photo up here and I’ll post this on the website and in the FB group for those listening.. interesting to finally get a good look at the much smaller applicator – as expected looks a lot like the Libre. Also interesting, all the PR for this has said, developed in partnership with Verily.. remember them? That was part of google, probably best known for saying they were going to develop a contact lens that would monitor glucose. I’ve reached out to Verily, love to know more about this partnership. Anyway, we’ve done a ton on G7, I’ll link up some of our recent conversations with the folks at Dexcom. They submitted to the US FDA at the end of 2021, no firm timeline on US approval.
https://www.medicaldevice-network.com/news/dexcom-ce-mark-g7-cgm-system/
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Some good news about living longer with chronic conditions, including diabetes. This was a 20-year British study that ended in 2011, so one caveat here, it doesn’t include COVID. Men gained 4-point-6 years of life expectancy; women gained 2-point-1. When it comes to disability-free life expectancy, men gained about a year less and women stayed the same. This included people with chronic conditions including those with diabetes. These researchers do point out that while they’d expect to see the same increase in the US – the lack of health and social safety net programs could make a negative difference here. But they point to CGM technology and better medication as making a big difference for those with diabetes.
https://www.healthline.com/health-news/why-people-with-chronic-conditions-such-as-diabetes-are-living-longer-without-disability#Cognitive-impairment-is-the-exception
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Children who develop type 1 diabetes show epi-genetic changes in the cells of their immune system long before the antibodies of the disease are detected in their blood. An epigenetic change affects how our genes work. Outside factors such as environmental, viral infections, are usually the cause. These researchers say these are previously unknown changes that signal the increased risk of developing type 1 and could give an even earlier indication than the anti-body marker tests available now.
https://www.news-medical.net/news/20220316/Epigenetic-changes-could-be-a-biomarker-for-early-detection-of-type-1-diabetes.aspx
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Could text-messaging with their doctors help people with type 2? A new team in Chicago is looking at text-based intervention in underserved communities. The intervention will deliver personalized information directly to patients through text messages, including reminders about self-monitoring and prescription refills, interactive office hours and general information about diabetes, motivational support and answers to frequently asked questions. These doctors say the idea is to create more opportunities for patients to meaningfully engage and reduce barriers by employing technology already in people’s hands.
https://today.uic.edu/an-sms-solution-for-type-2-diabetes
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Last week we told you about the effort by Civica RX to make affordable insulin. Civica, is a nonprofit generic pharmaceutical company. JDRF directed funds to this effort and CEO Aaron Kowalski wrote an op ed that I’ll link up. In it, he talks about the success Civica has had lowering the costs of other medications. We’ll have Kowalski on the show soon and I’ve reached out to Civica as well. This would lower the price to $35 a vial no matter your insurance. Congress still hung on a $35 co-pay cap for those with insurance.
https://www.healthline.com/diabetesmine/op-ed-jdrf-leader-on-insulin-affordability-for-all-americans
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Over in the UK they keep moving forward – covering all 400-thousand Britons with type 1 for the Libre CGM. Former guest of the podcast, Dr. Partha Kar, says everyone with type 1 will be able to get a CGM if they want one by the end of March. It will no longer be restricted by who doctors think need it the most. By the way, Briton means someone from England, Scotland or Wales. It’s the first time I’m using that word so UK friends.. let me know if I’ve got it right!
https://www.dailymail.co.uk/health/article-10606335/All-400-000-type-1-diabetic-Britons-offered-high-tech-implant.html
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Still a big need for diabetes help to Ukraine. A lot of the efforts are paying off – Insulin for Life showing that the supplies are on their way or have arrived. Spare a Rose reports that individual donations so far have totaled more than 115-thousand-dollars. I’ll keep linking up places to donate
https://www.jdrf.org/blog/2022/03/02/helping-the-diabetes-community-in-ukraine/
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Reaction to Pixar’s Turning Red. I loved this. I put out a call for photos of people seeing themselves in the movie’s tiny little moments of diabetes representation. Thanks to all who sent those in – you can see them on Diabetes Connections on Facebook and Twitter. And my Stacey Simms account on Instagram. It’s all just one account there.
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While Turning Red had diabetes in the background.. this week on the long format episode we’re talking about a movie that wants to put type 1 front and center. And it’s got the Star Trek community excited as well! Meet the Star Trek Discovery actor with type 1 who’s leading this effort.
Next week, we’re going on a deep dive about stem cell research with the folks at Viactye. They’re working on two fronts now.. encapsulation AND gene editing with the people at CRISPR.
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That’s In the News for this week.. if you like it, please share it! Thanks for joining me! See you back here soon.